Isa—rendered approximately EE-suh in English and EE-sah in Arabic and Turkish—stands at the intersection of several linguistic lineages, each imparting a distinct layer of meaning. In Arabic, ʿĪsā names the Qur’anic Jesus, conferring theological depth that travels eastward into Turkish usage; within Germanic languages it arose independently as a clipped feminine form of Isabella, Isadora, or Isolde, lending it a gentler, courtly pedigree. This dual provenance underwrites Isa’s classification as unisex and explains its steady, if understated, tenure in American records: first noted in 1925, the name has progressed from single-digit annual occurrences to more than two hundred newborns in 2024, an upward trajectory that mirrors the nation’s growing linguistic and cultural plurality rather than passing fashion. Compact yet sonorous, Isa benefits from worldwide phonetic transparency, and even finds an unexpected echo in aeronautical engineering, where ISA abbreviates the International Standard Atmosphere—an association that, while peripheral, reinforces the name’s modern, globally minded aura.
| Isa Boletini was an Albanian revolutionary commander and politician from Kosovo who played a leading role in the Albanian National Awakening. |
| Grand Ayatollah Isa Ahmed Qassim is Bahrain's leading Shia cleric and spiritual guide of the opposition group Al Wefaq. |
| Isa Kremer - Isabelle Kremer was a Russian Jewish soprano who published revolutionary poetry as a teenager in Odessa and sang opera in Europe before moving to the United States in 1924 to perform as a concert soloist. |
| Isa Guha is a former England cricketer who played in the 2005 and 2009 World Cups and now works as a sports TV commentator and radio broadcaster. |
| Isa Melikov is a celebrated Azerbaijani composer and producer whose hit songs and film soundtracks have been performed by top stars from Azerbaijan, the CIS and Europe, including Dima Bilan and Eurovision winners Eldar Gasimov and Nikki Jamal. |
| Isa Miranda was an Italian actress who found fame in Europe and Hollywood and won Best Actress at Cannes for The Walls of Malapaga. |
| Isa Mustafa is a retired Kosovar politician who served as mayor of Pristina, prime minister of Kosovo from 2014 to 2017, and longtime leader of the Democratic League of Kosovo. |
| Isa Molde is a Filipino volleyball star who plays for the Choco Mucho Flying Titans in the Premier Volleyball League. |
| Isa Sedigh served as Iran's minister of education and became the third president of the University of Tehran. |
| Isa Barzizza was an Italian actress with a career of more than six decades. |
| Isa Saharkhiz is an Iranian journalist and former press chief under President Khatami who was jailed for criticizing the regime after the 2009 election and freed in 2013. |
| Isa Hoes is a Dutch actress best known for playing Myriam van der Pol in the soap opera Goede tijden slechte tijden. |
| Isa Soares is a Portuguese journalist in London who anchors CNN International's weeknight show Isa Soares Tonight. |
| Isa Leshko - Isabella Leshko is an American fine art photographer known for her Elderly Animals series, which explores animal rights, aging and mortality. |
| Isa Mämmetgulyýew - Isa Mammetgulyyev is a Turkmen tennis player who reached a world ranking of 1115 in 2016, still the highest ever for a player from Turkmenistan. |